Our most advanced formulation for patients with acid-weakened enamel
Acid-weakened enamel can lead to enamel erosion.* Help your patients stop erosion by recommending a toothpaste designed to help:

- Repair microdamage and rebuild enamel strength1
- Actively repair acid-weakened enamel1
- Lock in vital minerals1
- Relieve tooth sensitivity1
*Due to dietary acids.

The science behind Pronamel Intensive Enamel Repair
New Pronamel Intensive Enamel Repair toothpaste is the most advanced enamel-care formulation in the Pronamel brand that both improves the natural remineralization process and inhibits demineralization.1
- Active ingredients are sodium fluoride (1150 ppm) and 5% w/w potassium nitrate
- Added inactive polymer locks in minerals and protects against acids, inhibiting demineralization and allowing more time to rebuild enamel strength1
- Added inactive lactate and controlled pH helps lock in fluoride and calcium, essential to rehardening enamel, deep into the surface of the tooth to more effectively promote fluoride uptake1
Delivers more fluoride deep into acid weakened enamel surfaces3



Dynamic secondary ion mass spectroscopy (DSIMS) images
of fluoride uptake to enamel surfaces in vitro
Adapted from Data on file. DSIMS analysis of fluoride uptake in treated human tooth enamel.
In vitro cross-sectional DSIMS images of enamel surface to compare in-depth penetration of fluoride.
†Crest ProHealth Clean Mint (0.454% stannous fluoride). US sourced in March 2018.
‡Colgate Enamel Health (1150 ppm fluoride). US sourced in March 2018.
Provides advanced protection with less enamel loss after 2 minutes of brushing4



3DP imaging reveals enamel loss vs other toothpastes at 2 minutes of brushing

Data on file. Surface roughness and material loss analysis of treated human tooth enamel using white light interferometry (WLI). The 3DP analysis of human enamel specimens measured the loss of material (step height) between tape-protected and exposed regions of the enamel, following a brushing treatment. Brushing with Pronamel Intensive Enamel Repair resulted in protection from tissue loss due to demineralization and surface wear, vs Crest ProHealth and Colgate Enamel Health.
†Crest ProHealth Clean Mint (0.454% stannous fluoride). US sourced in March 2018.
‡Colgate Enamel Health (1150 ppm fluoride). US sourced in March 2018.
References: 1. Data on file. Sensodyne Pronamel Intensive Enamel Repair toothpaste product claims. GlaxoSmithKline; Warren, NJ. 2. Zero DT, Lussi A. Erosion–chemical and biological factors of importance to the dental practitioner. Int Dent J. 2005;55(4):285-290. 3. Data on file. DSIMS analysis of fluoride uptake in treated human tooth enamel. GlaxoSmithKline; Warren, NJ. 4. Data on file. Surface roughness and material loss analysis of treated human tooth enamel using white light interferometry (WLI). GlaxoSmithKline; Warren, NJ.